Ma. Mcnally et al., ATTITUDES TO, AND UTILIZATION OF, LOW-MOLECULAR-WEIGHT HEPARINS IN JOINT REPLACEMENT SURGERY, Journal of the Royal College of Surgeons of Edinburgh, 42(6), 1997, pp. 407-409
A postal survey was carried out to determine the attitudes to the use
of low molecular weight heparin (LMWH) in joint replacement among two
representative groups of orthopaedic surgeons practising in the UK. 72
% of hip surgeons and 51% of knee surgeons replying had used LMWHs for
deep vein thrombosis prophylaxis in joint replacement patients. Of th
ese, 48% had discontinued LMWH use due to bleeding complications. Amon
g those continuing to use LMWHs, 88% had witnessed excessive bruising
around the wound and 53% had experienced increased wound bleeding or h
aematomas. Although LMWHs have been shown to reduce post-operative thr
omboembolism in these groups, clinical experience has revealed an incr
eased incidence of bleeding complications associated with their use. T
his has prevented their routine use in joint replacement, as was the c
ase with unfractionated heparin in the past.