Rapid progression of arterial disease may occur between out-patient di
agnostic arteriography and therapeutic angioplasty. We have studied th
e incidence of this complication in our institution. Sixty-seven conse
cutive out-patient arteriograms were assessed. Thirty-four patients we
re re-admitted for angioplasty within a median interval of 4 weeks (ra
nge 5 days-3 months). We compared immediate preangioplasty arteriogram
s with the out-patient images. Twenty-five pairs of films showed disea
se progression. Three patients showed new disease, one remote from the
site of the arterial lesion and two in the opposite limb. Six patient
s showed marked progression of the original disease. The policy of del
ayed treatment after out-patient arteriography may require reconsidera
tion hi the light of our complication rate of 18%.