A four-step synthetic approach to substituted linear and angular benzo
furocoumarins is described. Starting from 5-methoxyresorcinol, this ap
proach afforded good yields of benzopsoralen (7), benzoangelicine (8),
and benzoallopsoralen (11), which bear easily hydrolysed methoxy grou
ps and thus allow access to other substituted compounds with potential
as photochemotherapeutic agents.