CARCINOGEN-PROTEIN ADDUCTS IN BLOOD-SERUM OF WORKERS FROM THE RUBBER INDUSTRY

Authors
BELOKHVOSTOVA AT POTAPENKOVA LS KAVERZNEVA TT MISHUKOV VI KHUDOLEY VV
Citation
At. Belokhvostova et al., CARCINOGEN-PROTEIN ADDUCTS IN BLOOD-SERUM OF WORKERS FROM THE RUBBER INDUSTRY, Eksperimental'naa onkologia, 19(4), 1997, pp. 284-288
Citations number
20
Journal title
Eksperimental'naa onkologia → ACNP
ISSN journal
02043564
Volume
19
Issue
4
Year of publication
1997
Pages
284 - 288
Database
ISI
SICI code
0204-3564(1997)19:4<284:CAIBOW>2.0.ZU;2-R
Abstract
The presence of carcinogen-protein adducts (CPA) contained exogenic ca rcinogens benzidine and 2-naphthylamine as well as endogenic carcinoge n 3-oxyanthranylic acid was detected in blood serum of 7035 workers of the rubber industry by the method of double radial immunodiffusion in agar. CPA were revealed in 1324 persons (18,8%) which represent a gro up of high oncological risk. The role of CPA as high informative biolo gical markers of cancer risk is discussed.