AN IMPROVED SYNTHESIS OF 2,3-DISUBSTITUTED 4-(3H)-QUINAZOLINONES FROM2-ACYLAMINO (N-ARYL) BENZAMIDES

Authors
ACHARYA DP CHATTOPADHYAY S
Citation
Dp. Acharya et S. Chattopadhyay, AN IMPROVED SYNTHESIS OF 2,3-DISUBSTITUTED 4-(3H)-QUINAZOLINONES FROM2-ACYLAMINO (N-ARYL) BENZAMIDES, Indian Journal of Heterocyclic Chemistry, 7(2), 1997, pp. 101-104
Citations number
20
Journal title
Indian Journal of Heterocyclic Chemistry → ACNP
ISSN journal
09711627
Volume
7
Issue
2
Year of publication
1997
Pages
101 - 104
Database
ISI
SICI code
0971-1627(1997)7:2<101:AISO24>2.0.ZU;2-I
Abstract
2-Acylamino (N-aryl) benzamides (3a,h) on refluxing with TsOH in benze ne or acetonitrile solution undergo smooth cyclodehydration to 2,3-dis ubstituted 4-(3H)-quinazolinones (4a-h). A convenient procedure for co nverting isatoic anhydride (1) to 2-amino (N-aryl/alky) benzamides (2) is also reported.