RECENT ADVANCES IN THE BIOLOGY OF CENTRAL-NERVOUS-SYSTEM TUMORS

The failure of conventional therapies for many malignant brain tumors has led to a search for more promising alternatives. Recent advances h ave elucidated a variety of biological factors that act to determine t he growth and invasiveness of central nervous system tumors. Such fact ors include aberrations in the regulation of the cell cycle, apoptosis , and interactions with the host microenvironment. Such insights shoul d translate into novel interventions so that more meaningful outcomes can be achieved in patient care in the future. (C) Rapid Science Publi shers.