ELICITATION KINETICS OF TAXANE PRODUCTION IN SUSPENSION-CULTURES OF TAXUS-BACCATA PENDULA

Authors
MOON WJ YOO BS KIM DI BYUN SY
Citation
Wj. Moon et al., ELICITATION KINETICS OF TAXANE PRODUCTION IN SUSPENSION-CULTURES OF TAXUS-BACCATA PENDULA, Biotechnology techniques, 12(1), 1998, pp. 79-81
Citations number
10
Categorie Soggetti
Biothechnology & Applied Migrobiology","Biochemical Research Methods
Journal title
Biotechnology techniques → ACNP
ISSN journal
0951208X
Volume
12
Issue
1
Year of publication
1998
Pages
79 - 81
Database
ISI
SICI code
0951-208X(1998)12:1<79:EKOTPI>2.0.ZU;2-M
Abstract
Methyl jasmonate increased taxane production in suspension cultures of Taxus baccata Pendula. Time course changes of taxane production after methyl jasmonate addition were different from normal kinetics without elicitation. Baccatin III and 10-deacetyl baccatin III were detected first and paclitaxel, 10-deacetyl taxol and cephalomanine followed eac h other in sequence. Paclitaxel was not a dead-end metabolite.