HEPATOBLASTOMA IN A DOG

A hepatoblastoma was found in a 13-year-old female Maltese dog. Histol ogically, the tumor showed a wide trabecular pattern and was frequentl y accompanied with vascular lake formation. Tumor cells were positive for cytokeratin and neuron specific enolase, but negative for chromogr anin. Electronmicroscopically, tumor cells were accompanied with conti nuous basement membrane and had poorly developed desmosomes. Sinusoida l endothelia had fenestration and were surrounded by myofibroblast-lik e cells. To the best of our knowledge, this paper is the first report of morphological studies on canine hepatoblastoma.