S. Belikov et al., UNCURVED-DNA SIGNALS ARE IMPORTANT FOR TRANSLATIONAL POSITIONING OF NUCLEOSOMES, Journal of biomolecular structure & dynamics, 15(3), 1997, pp. 625-630
We describe here a possible mechanism for non-random arrangement of nu
cleosomes along genomic DNA by short stretches of uncurved DNA. Availa
ble biochemical data on nucleosome positioning on different DNA sequen
ces were analyzed. A strong correlation between location of nucleosome
borders and location of uncurved sequences along DNA was observed. Te
sted sequences include satellites, 5S RNA genes and 5' regions of diff
erent genes.