The contribution of the mammillary region to several classes of learni
ng and memory has been reviewed. There is considerable evidence that l
esions of this region of the brain impair performance on tasks that re
quire memory for locations that an animal has visited, but that the de
ficit depends both on the amount of damage within the region and the d
ifficulty of the task. Such lesions, however, do not appear to impair
performance on a variety of spatial conditional associative learning t
asks which require the animal to form an association between a place o
r a scene and a stimulus embedded within it. In addition, damage to th
e region of the mammillary bodies does not impair the ability to learn
a variety of non-spatial memory tasks. These studies suggest that the
mammillary region may play a selective role in certain types of spati
al learning and memory. (C) 1997 Elsevier Science Ltd.