Motivation: The Human cDNA Database (HCD) at the Institute for Genomic
Research (TIGR) is the most complete, non-redundant and structured co
llection of human expressed DNA sequences available to date. Sequences
and other data can be retrieved by users having opened an account at
HCD/TIGR. A HCD search involves composing and sending queries one by o
ne and this can become time consuming if many queries must be sent. Mo
reover, a large amount of time is required thereafter to process the r
esults. Results: The HCDSearch system described here automatically com
poses and sends the queries by e-mail using information provided in a
text file; it also greatly accelerates the processing of results, gene
rating lists of HCD numbers and library identifiers in a format that r
enders them very easy to examine. The programs run on Unix platforms.