STUDIES ON ANTITUSSIVE ACTIVITY OF DRYMARIA-CORDATA WILLD (CARYOPHYLLACEAE)

Authors
MUKHERJEE PK SAHA K BHATTACHARYA S GIRI SN PAL M SAHA BP
Citation
Pk. Mukherjee et al., STUDIES ON ANTITUSSIVE ACTIVITY OF DRYMARIA-CORDATA WILLD (CARYOPHYLLACEAE), Journal of ethnopharmacology, 56(1), 1997, pp. 77-80
Citations number
8
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Journal of ethnopharmacology → ACNP
ISSN journal
03788741
Volume
56
Issue
1
Year of publication
1997
Pages
77 - 80
Database
ISI
SICI code
0378-8741(1997)56:1<77:SOAAOD>2.0.ZU;2-P
Abstract
The methanol extract of Drymaria cordata Willd. was investigated for i ts effect on a cough model induced by sulfur dioxide gas in mice. It e xhibited significant antitussive activity when compared with the contr ol in a dose-dependent manner. The antitussive activity of the extract was comparable to that of codeine phosphate, a prototype antitussive agent. The D. cordata extract (100, 200, 400 mg/kg) showed 11.6%, 31.6 % and 51.5% inhibition of cough with respect to the control group. (C) 1997 Elsevier Science Ireland Ltd.