A. Caballero et al., SPONTANEOUS DISAPPEARANCE OF ELSCHNIG PEARLS AFTER NEODYMIUM-YAG LASER POSTERIOR CAPSULOTOMY, Journal of cataract and refractive surgery, 23(10), 1997, pp. 1590-1594
Posterior capsule opacification (PCO) from Elschnig pearl formation is
a common complication of extracapsular cataract extraction. After PCO
treatment by neodymium:YAG (Nd:YAG) laser posterior capsulotomy, Elsc
hnig pearls may undergo hyperproliferation at the edge of the capsulot
omy, which may close it. We have seen six eyes in five patients who pr
esented with spontaneous disappearance of Elschnig pearls, resulting i
n a perfectly clear posterior capsule several years after an Nd:YAG po
sterior capsulotomy. Possible causes include (1) falling of pearls int
o the vitreous through the capsulotomy; (2) phagocytosis of pearls by
macrophages; (3) cell death by apoptosis.