We present observations of CO J = 1-0 emission toward 3C 391, a supern
ova remnant whose radio continuum and X-ray emission suggest evolution
near a strong density gradient in the surrounding medium. The CO maps
reveal that the remnant is located at the edge of a molecular cloud,
and the CO emission shows a striking correspondence with the ''breakou
t'' morphology of the remnant traced by radio continuum emission. Thes
e data support the idea that the progenitor star exploded within a den
se molecular cloud and that the supernova blast wave has now broken ou
t through the cloud boundary. Bright radio emission coincident with st
rong CO emission suggests that the blast wave accelerates electrons to
energies of at least 20 GeV, even as it moves into dense neutral mate
rial.