GROWTH-FACTORS AND HEMATOPOIETIC STEM-CELLS

Authors
VEIBY OP MIKHAIL AA SNODGRASS HR
Citation
Op. Veiby et al., GROWTH-FACTORS AND HEMATOPOIETIC STEM-CELLS, Hematology/oncology clinics of North America, 11(6), 1997, pp. 1173
Citations number
141
Categorie Soggetti
Oncology,Hematology
Journal title
Hematology/oncology clinics of North America → ACNP
ISSN journal
08898588
Volume
11
Issue
6
Year of publication
1997
Database
ISI
SICI code
0889-8588(1997)11:6<1173:GAHS>2.0.ZU;2-K
Abstract
The hematopoietic system is mediated in part by cell-to-cell interacti ons and soluble mediators or growth factors (cytokines). A large numbe r of cytokines directly and potently control hematopoietic stem and pr ecursor cell proliferation and differentiation. This review focuses on the recent studies devoted to the role of cytokines in the ex vivo ex pansion and differentiation of hematopoietic stem and precursor cells.