There is considerable clinical and immunologic evidence for a probable
role of allergy in the production of the symptoms of Meniere's diseas
e. The endolymphatic sac is the seat of immune reactivity in the inner
ear. Inhalant and food allergies have been linked with symptoms of Me
niere's disease, and many of the clinical characteristics of Meniere's
disease suggest an underlying autoimmune etiology. A significant perc
entage of patients with Meniere's disease and allergy show improvement
in their symptoms of tinnitus and vertigo when receiving specific all
ergy therapy.