Me. Hoffer et al., USE OF SUSTAINED-RELEASE VEHICLES IN THE TREATMENT OF MENIERES-DISEASE, Otolaryngologic clinics of North America, 30(6), 1997, pp. 1159
Over the years, a variety of empirical regimens have evolved using int
ratympanic gentamicin to treat the vertigo associated with Meniere's d
isease. Although these regimens have been effective, their application
is not without risk. Many of the problems associated with intratympan
ic medications could be overcome with the use of a sustained release v
ehicle. This article examines the role of such vehicles in the treatme
nt of Meniere's disease and how sustained release vehicles might impac
t future treatment for this disabling disease.