In order to exploit the peculiar characteristics of synchrotron radiat
ion for X-ray mammography purposes, monochromatic X-ray beams of selec
ted energies from 16 keV to 22 keV have been used for the first time e
ver to obtain mammograms of surgically removed breast specimens contai
ning cancer nodules. The apparatus devised particularly in view of a p
ossible clinical applications, allowed large breast specimens fixed in
space to be exposed to a vertical scanning X-ray beam. The mammograms
obtained with synchrotron radiation, compared with those made using a
traditional mammographic unit had higher contrast and better resoluti
on demonstrating, in all the cases studied, a high capability to displ
ay a large number of structures inside the neoplastic lesions. Thermol
uminescent dosimeters were used to determine the doses. The average me
an glandular doses, at 17 keV and 18 keV, were 1.56 mGy and 0.84 mGy,
respectively, comparable with the value of 1.41 mGy delivered with the
conventional grid apparatus.