A CASE OF EPSTEIN-BARR-VIRUS INFECTION WITH EXOPHTHALMOS AND OCULAR MUSCLE SWELLING

Authors
SUGIYAMA K ITO M ICHIMI R HIGASHIKAWA M KAWASAKI H KOMADA Y SAKURAI M WAKIGUCHI H KIKUTA H FUKAYAMA M
Citation
K. Sugiyama et al., A CASE OF EPSTEIN-BARR-VIRUS INFECTION WITH EXOPHTHALMOS AND OCULAR MUSCLE SWELLING, Acta Paediatrica Japonica Overseas Edition, 39(6), 1997, pp. 694-697
Citations number
8
Categorie Soggetti
Pediatrics
Journal title
Acta Paediatrica Japonica Overseas Edition → ACNP
ISSN journal
03745600
Volume
39
Issue
6
Year of publication
1997
Pages
694 - 697
Database
ISI
SICI code
0374-5600(1997)39:6<694:ACOEIW>2.0.ZU;2-4
Abstract
A 14-year-old girl with Epstein-Barr virus (EBV) infection developed e xophthalmos and ocular muscle swelling. The EBV genome was detected in T lymphocytes taken from the submandibular gland, temporal muscle and cervical lymph nodes. A surface marker analysis of her peripheral blo od demonstrated that CD45RO-positive T lymphocytes were strongly activ ated. Immunosuppressive treatment, including steroid and cyclophospham ide, was effective in improving the symptoms. Immunosuppressive therap y may be included as the choice of treatment for EBV infection.