ANTHELMINTIC RESISTANCE IN NEMATODE PARASITES FROM GOATS IN SPAIN

In a flock of cashmere goats sited in Asturias (NW, Spain) diminished efficacy was observed following treatment with netobimin and consequen tly a study to demonstrate the existence of anthelmintic resistance an d the species of nematode involved was conducted. Results from faecal egg count reduction tests before and after treatment with netobimin or ivermectin showed efficacies of 89.4 (81.8-94.8) and 99.7% (93.9-99.9 %), respectively. Teladorsagia circumcincta was found to be the domina nt species involved in netobimin resistance. Effective dose (ED50) val ues in the egg hatch assay of 0.22 mu g thiabendazole ml(-1) confirmed the existence of benzimidazole carbamate resistant nematodes. To the best of our knowledge, this is the first report on the existence of an thelmintic resistant nematodes from ruminants in Spain. (C) 1997 Elsev ier Science B.V.