Objectives: The aim of this study was to determine ia) whether delay i
n femur fracture stabilization beyond twenty-four hours in patients wi
th head injury increased the risk of pulmonary complications and (b) w
hether immediate (up to twenty-four hours) femur fracture stabilizatio
n increased the risk of central nervous system (CNS) complications. De
sign: Retrospective analysis. Materials and Methods: Thirty-two patien
ts with femur fracture and head injury were identified. Fourteen under
went immediate sta bilization of their fractures, and eighteen underwe
nt delayed (fourteen patients) or no (four patients) stabilization of
their fractures. Results: In the immediate stabilization group, five p
atients had severe head injuries [Glasgow Coma Scan (GCS) less than or
equal to 8] and nine had mild head injuries (GCS > 8). In the mild he
ad injury group, no patient had a pulmonary complication and one had a
CNS complication. In the severely head-injured group, one patient had
a pulmonary complication and no patient had a CNS complication. In th
e delayed stabilization group, six patients had mild head injuries (GC
S > 8) and twelve had severe head injuries (GCS less than or equal to
8). In the mildly head injured group, one patient had a pulmonary comp
lication, two patients had CNS complications, and one patient died. In
the severely head injured group, nine patients had pulmonary complica
tions, three patients had CNS complications, and one patient died. Log
istic regression identified delay in femur stabilization as the strong
est predictor of pulmonary complication (p = 0.0042), followed by seve
rity of chest Abbreviated Injury Score (AIS; p = 0.0057) and head AIS
(p = 0.0133). Delaying fracture stabilization made pulmonary complicat
ions forty-five times more likely. Each point increase in the chest AI
S and head/neck AIS increased the risk of pulmonary complication by 30
0 percent and 500 percent, respectively. A statistically significant p
redictor of CNS complications could not be identified by using logisti
c regression. Conclusion: Delay in stabilization of femur fracture in
head-injured patients appears to increase the risk of pulmonary compli
cations. However, due to selection bias in this patient sample, this q
uestion cannot be definitively answered. Early fracture stabilization
did not increase the prevalence of CNS complications.