PRIMARY INTRAVASCULAR LYMPHOMATOSIS ASSOCIATED WITH MYCOBACTERIUM-MARINUM

Intravascular lymphomatosis (;VL) is a rare condition in which neoplas tic cells preferentially infiltrate blood vessels of the central nervo us system. Nonspecific symptoms associated with IVL include dementia, seizures, and multifocal cerebrovascular events. IVL was discovered at autopsy of a patient whose neurological deficits were predated by a p articularly aggressive form of Mycobacterium marinum soft-issue infect ion. it is speculated that IVL may have had an occult effect on the pa tient's cell-mediated immunity that predisposed him to this normally i nnocuous mycobacteria.