KINETICS OF PANCREATIC EXOCRINE SECRETION AND PLASMA GUT REGULATORY PEPTIDE RELEASE IN RESPONSE TO FEEDING IN PRERUMINANT AND RUMINANT CALVES

Citation
G. Ledrean et al., KINETICS OF PANCREATIC EXOCRINE SECRETION AND PLASMA GUT REGULATORY PEPTIDE RELEASE IN RESPONSE TO FEEDING IN PRERUMINANT AND RUMINANT CALVES, Comparative biochemistry and physiology. Section A: Comparative physiology, 117(2), 1997, pp. 245-255
Citations number
57
Categorie Soggetti
Physiology,Biology
Journal title
Comparative biochemistry and physiology. Section A: Comparative physiology
ISSN journal
10956433 → ACNP
Volume
117
Issue
2
Year of publication
1997
Pages
245 - 255
Database
ISI
SICI code
1095-6433(1997)117:2<245:KOPESA>2.0.ZU;2-3
Abstract
Pancreatic exocrine secretion and plasma cholecystokinin, gastrin, sec retin, and somatostatin concentrations were examined in relation to fe eding in 70- re, 120-day-old preruminant and ruminant calves. The appa ratus used was designed to immediately re-infuse the animal's own panc reatic juice and to carry out accurate measurements of the juice flow in real time and to take samples. In the preruminants, pancreatic juic e, protein, and trypsin flows increased from 45 min before and until 1 5 min after the meal and decreased sharply thereafter over a period of 30 min, while protein and trypsin concentrations peaked after feeding . A significant increase in plasma gastrin and cholecystokinin (CCK), a fall in secretin and no change in somatostatin were observed after m ilk ingestion. By contrast, in the ruminants, feeding had no effect on the pancreatic secretion and on the plasma concentrations of these pe ptides. Similar and simultaneous patterns of juice flow and secretin, as well as of protein and trypsin concentrations, CCK and gastrin, cou ld support the hypothesis that these gut regulatory peptides play a si gnificant role in the regulation of the pancreatic function. In prerum inant calves, the existence of cephalic, gastric and intestinal phases is discussed. In the ruminants, that of the ruminal phase is question able. (C) 1997 Elsevier Science Inc.