The format of the TRRD complies with the model of hierarchical organiz
ation of transcription regulatory regions of eukaryotic genes, The cur
rent version of TRRD covers more than 300 genes, with several large se
ctions concerning different important systems of functionally linked g
enes. Each such section contains formalized information on the structu
re of regulatory regions in a specially designed format, and nonformal
ized information in textual and graphic form. Integration is achieved
with the WWW hypertext tools. We describe a relational model of the da
tabase and ways far its integration with other databases, first of all
TRANSFAC and COMPEL. TRRD is accessible at http//www.bionet.nsc.ru/TR
RD/.