REGULATION OF TRANSCRIPTION OF LIPID-METABOLISM GENES - DESCRIPTION IN THE TRRD DATABASE

Regulation of transcription of lipid metabolism genes is described acc ording to the information accumulated in the LM-TRRD database (Lipid M etabolism-Transcription Regulatory Regions Database). Data on 52 genes of the lipid metabolism system are presented in the current release o f the LM-TRRD database. Besides information about regulation of transc ription of these genes in the TRRD format? there are also hypertexts w ith additional data. The composition of transcription factors involved in the lipid metabolism gene regulation was analyzed. The block struc ture of regulatory regions of these genes was studied. The gene networ ks of two subsystems are described. One of them is involved in the oxi dation of fatty acids, whereas the other provides for homeostasis of c holesterol. The LM-TRRD database is accessible via Internet at http:// www.bionet.nsc.ru/TRRD/.