Ea. Ananko et al., MECHANISMS OF TRANSCRIPTION REGULATION OF INTERFERON-INDUCIBLE GENES - DESCRIPTION IN THE IIG-TRRD INFORMATION-SYSTEM, Molecular biology, 31(4), 1997, pp. 592-604
The pilot variant of IIG-TRRD database is presented containing informa
tion on more than 60 interferon-inducible genes, Mechanisms of signal
transduction from receptors to target genes are analyzed, and features
of organization of regulatory regions and transcriptional regulation
of interferon-inducible genes are described. Functions of some interfe
ron-inducible proteins are considered. Principles of organization of g
ene network regulating functioning of the interferon system are descri
bed. IIG-TRRD database is available to Internet users (http://www.bion
et.nsc.ru/TRRD).