AUTORADIOGRAPHIC DISTRIBUTION OF BRAIN-STEM SUBSTANCE-P BINDING-SITESIN HUMANS - ONTOGENIC STUDY AND RELATION TO SUDDEN-INFANT-DEATH-SYNDROME (SIDS)

Authors
JORDAN D KERMADI I RAMBAUD C BOUVIER R DIJOUD F MARTIN D KOPP N
Citation
D. Jordan et al., AUTORADIOGRAPHIC DISTRIBUTION OF BRAIN-STEM SUBSTANCE-P BINDING-SITESIN HUMANS - ONTOGENIC STUDY AND RELATION TO SUDDEN-INFANT-DEATH-SYNDROME (SIDS), Journal of neural transmission, 104(10), 1997, pp. 1101-1105
Citations number
5
Journal title
Journal of neural transmission → ACNP
ISSN journal
03009564
Volume
104
Issue
10
Year of publication
1997
Pages
1101 - 1105
Database
ISI
SICI code
0300-9564(1997)104:10<1101:ADOBSB>2.0.ZU;2-I
Abstract
The precise distribution of substance P (SP) binding sites in the huma n brainstem was investigated in normal cases (3 fetuses and 24 newborn s) and in 9 cases of Sudden Infant Death Syndrome (SIDS) by in vitro q uantitative autoradiography. We discussed the widely but uneven distri bution of SP binding sites as regards to the role of SP in brainstem c ardio-respiratory ontogenic control and its possible involvement in SI DS.