Objective: This study aimed to describe results of glaucoma surgeries
performed at one institution over the past 20 years in children with a
phakia, aniridia, anterior segment dysgenesis, and other secondary gla
ucomas. Design: The study design was a retrospective review. Participa
nts: Fifty-eight eyes of 40 patients were studied. Intervention: Trabe
culectomy with or without mitomycin C, Molteno implantation, goniotomy
, sclerostomy, endolaser cyclophotocoagulation, and cyclocryotherapy w
ere performed, Main Outcome Measures: Intraocular pressure (IOP) contr
ol, defined as complete success (IOP less than or equal to 21 without
medications) or qualified success (IOP less than or equal to 25 withou
t medications or IOP less than or equal to 21 with medications) and po
stoperative visual acuity stability were assessed. Results: One hundre
d thirty surgical procedures were performed on 58 eyes of 40 patients;
follow-up averaged 7.3 years. Intraocular pressure control was achiev
ed in 40 (70%) of 57 eyes after 1 or more procedures, Intraocular pres
sure control and stabilization of visual acuity and optic disc appeara
nce were achieved in 28 (51%) of 55 eyes, Five eyes had significant po
stoperative complications, Trabeculectomy with mitomycin C controlled
IOP on last visit in 8 of 13 eyes with aphakic glaucoma. Conclusions:
Surgical intervention can control IOP and prevent visual loss in child
ren with secondary glaucomas. In the authors' experience, a filtering
procedure is the most effective treatment in aphakic glaucoma and ante
rior segment dysgenesis.