U. Spetzger et al., IMMEDIATE POSTOPERATIVE CT CONTRAST ENHANCEMENT FOLLOWING SURGERY OF CEREBRAL TUMORAL LESIONS, Journal of computer assisted tomography, 22(1), 1998, pp. 120-125
Purpose: Our goal was to evaluate the immediate postoperative contrast
enhancement behavior of cerebral lesions and to gain further informat
ion about contrast enhancement in patients under general anesthesia. M
ethod: In the early postoperative period, CT scans with and without co
ntrast medium were performed in 46 patients. The time interval between
surgery and postoperative CT imaging ranged from 1 to 7.5 h (mean 4 h
). Nineteen patients were under general anesthesia during CT investiga
tion. Results: In the early postoperative period, contrast medium leak
age into the tumor resection cavity was noted In 14 patients (30%). An
other phenomenon that was observed was the appearance of a strong dema
rcation and distinct contrast of gray against white matter in 24 patie
nts (52%). This characteristic, global contrast enhancement of the cer
ebral cortex, occurred in 17 of 19 patients (89%) investigated under g
eneral anesthesia. Conclusion: In immediate postoperative CT scans, co
ntrast medium leakage due to extravasation of contrast medium into the
tumor resection cavity can be detected early. Moreover, a global cont
rast enhancement of the cerebral cortex can be detected as a frequent
pattern in patients investigated under general anesthesia.