ANIONIC MANGANESE MESO-TETRAPHENYL PORPHINE OLIGNUCLEOTIDE CONJUGATES- SYNTHESIS AND UTILIZATION IN CHEMILUMINESCENT DNA-PROBE DETECTION/

Authors
SCHUBERT F KLUTSCH T CECH D
Citation
F. Schubert et al., ANIONIC MANGANESE MESO-TETRAPHENYL PORPHINE OLIGNUCLEOTIDE CONJUGATES- SYNTHESIS AND UTILIZATION IN CHEMILUMINESCENT DNA-PROBE DETECTION/, Nucleosides & nucleotides, 16(3), 1997, pp. 277-289
Citations number
20
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
3
Year of publication
1997
Pages
277 - 289
Database
ISI
SICI code
0732-8311(1997)16:3<277:AMMPOC>2.0.ZU;2-4
Abstract
The synthesis and application of oligodeoxynucleotides derivatized by the water-soluble anionic )-5-(4-carboxyphenyl)-10,15,20-tris-(4-sulph onato- phenyl)-porphine complex are described. These conjugates were f ound to be potent catalysts for the chemiluminescent oxidation of lumi nol, which in turn favour their application as non-radioactive DNA pro bes.