The ethyl acetate fraction (EA) from the residue of an 85% ethanol ext
ract of the latex of Euphorbia royleana (Euphorbiaceae) was investigat
ed for antipyretic and analgesic properties, The results showed a dose
related peripheral analgesic effect, The fraction assayed exhibited a
significant antipyretic effect in hyperthermic rats and rabbits, The
oral LD50 was more than 2 g/kg in rats and mice. (C) 1997 John Wiley &
Sons, Ltd.