E. Martinotti et al., PHARMACOLOGICAL ACTION OF AQUEOUS CRUDE EXTRACTS OF ARTEMISIA-VERLOTORUM LAMOTTE (COMPOSITAE), PTR. Phytotherapy research, 11(8), 1997, pp. 612-614
The pharmocological study of the responses evoked by a dried aqueous e
xtract of Artemisia verlotorum on different guinea-pig and rat isolate
d organs in vitro, suggests a possible muscarinic activity as a cause
of the antihypertensive activity. The ability of atropine, in ileum pr
eparations, and of N-omega-nitro L-arginine methyl ester, in aortic pr
eparations, to inhibit the plant effects seems to confirm the muscarin
ic nature of the responses. (C) 1997 John Wiley & Sons, Ltd.