MULTILOBULAR OSTEOCHONDROSARCOMA IN 39 DOGS - 1979-1993

Thirty-nine, older, large-breed dogs with multilobular osteochondrosar coma (MLO) each presented primarily with a fixed mass involving the fl at bones of the skull. Twenty-five dogs were treated with surgical res ection alone, nine were treated with adjuvant therapy and five were no t treated. Forty-seven percent of dogs treated had local tumor recurre nce, and 56% had metastasis. Median time to recurrence, median time to metastasis, and median survival time were 797, 542, and 797 days, res pectively. Histological grade, surgical margins, and tumor location af fected outcome. Long-term remission can be obtained with aggressive tr eatment of MLO, although if is locally invasive and moderately metasta tic.