D. Schellenberg et al., INFLUENCE OF THORACIC CONFORMATION AND GENETICS ON THE RISK OF GASTRIC DILATATION-VOLVULUS IN IRISH-SETTERS, The Journal of the American Animal Hospital Association, 34(1), 1998, pp. 64-73
Body measurements, history of gastric dilatation-volvulus (GDV), and o
ther data were obtained for 155 Irish setters at the 1994 National Spe
cialty Show. The dogs ranged in age from 6.5 months to 12.4 years (mea
n+/-standard deviation [SD] 3.6+/-2.6 years); 11 (7%) of the dogs had
histories of GDV. Gastric dilatation-volvulus risk increased 33% for e
ach year of age (p of 0.01). Dogs with the deepest thorax relative to
width (ratio range, 1.61 to 1.85) had a significantly greater GDV risk
than those with the shallowest thorax (ratio range, 1.20 to 1.50); th
e odds ratio was 8.45; the 95% confidence limits were 1.44 to 49.57; a
nd the p value equaled 0.02. Having a relative (particularly a parent)
with GDV also increased GDV risk, Five-generation pedigrees yielded a
significantly higher mean coefficient of relationship for the 11 dogs
with GDV than for the 11 dogs without GDV.