IN-VIVO INVESTIGATION OF STRESS SUSCEPTIB ILITY IN PIG BY MEANS OF MAGNETIC RESONANCE-SPECTROSCOPY

P-31 nuclear magnetic resonance spectroscopy was performed on 19 to 55 kg weighing pigs of different MHS genotypes to study the changes of p hosphorus components (inorganic phosphate -P-i, phosphocreatine - PCr and adenosine triphosphate-ATP) of muscle metabolism as well as intram uscular pH under application of halothane. Aim of the present study wa s to observe the changes in energy metabolism and to perform a compari son with also measured blood parameters. Both, NN and Nn pigs did not show any changes during halothane exposure in phosphorus spectra, but in all animals a partially metabolicly compensated respiratoric acidos is was found. In all MHS positive pigs a rapid fail of PCr and a corre sponding raise of Pi levels in muscle was observed.