BCG SPECIFICITY OF AN INHIBITORY SERIC FACTOR FROM TUBERCULOSIS ANERGIC PATIENTS THAT ACTS ON NONADHERENT PPD REACTIVE CELLS

Authors
MEJIALOPEZ H MARTINEZGARCIA LG ZENTENO E SALAZAR MA SELMAN M TAYLOR ML
Citation
H. Mejialopez et al., BCG SPECIFICITY OF AN INHIBITORY SERIC FACTOR FROM TUBERCULOSIS ANERGIC PATIENTS THAT ACTS ON NONADHERENT PPD REACTIVE CELLS, Immunological investigations, 26(3), 1997, pp. 323-331
Citations number
12
Categorie Soggetti
Immunology
Journal title
Immunological investigations → ACNP
ISSN journal
08820139
Volume
26
Issue
3
Year of publication
1997
Pages
323 - 331
Database
ISI
SICI code
0882-0139(1997)26:3<323:BSOAIS>2.0.ZU;2-5
Abstract
The effect of tuberculosis anergic immune sera adsorbed with BCG was s tudied on cocultures of adherent and non-adherent cells from PPD+ tube rculosis patient (TBP PPD+). This effect on the cocultures was quantif ied by lymphocyte transformation (LT) test using PPD as antigen. Only those cocultures with non-adherent cells from TBP PPD+ patients treate d with anergic sera, inhibited the LT response induced by PPD, whereas sera adsorption with BCG eliminated the inhibitory effect.