The holmium:YAG laser fragments stones of all compositions effectively
. However, damage to ureteral guidewires by the laser has been describ
ed, including in one of our own patients, in whom such damage resulted
in morbidity. The purpose of this study was to characterize the inter
action of Ho:YAG energy with guidewires in vitro. Seven ureteral guide
wires were tested in a waterbath. The 365-mu m Ho:YAG laser fiber was
placed at defined distances (0, 1, 2, 4, and 5 mm) from the guidewire.
All guidewires were tested at angles of 0 degrees, 45 degrees, and 70
degrees from normal incidence. The minimum energy setting that result
ed in structural damage to the guidewires was detected by endoscopic v
ideo monitoring. All guidewires were susceptible to Ho:YAG laser damag
e at modest energy settings. The energy required to produce visual dam
age varied inversely with the square of the distance of the laser fibe
r from the guidewire. At a distance of 5 mm, none of the guidewires wa
s damaged, even at energy settings of 2.8 J (the maximum output from t
he laser). The energy required to induce guidewire damage varied with
the inverse of the cosine of the incident angle. The results demonstra
te that no guidewire is immune from Ho:YAG laser damage when the fiber
and guidewire are in contact. Caution must be exercised when operatin
g the Ho:YAG laser near a guidewire, and guidewire integrity should be
assured by the surgeon. Generally, the energy required to induce guid
ewire damage exceeded lithotripsy levels at distances >1 mm and with h
igher incident angles, implying a reasonable margin of safety during u
reteroscopy. The pattern of energy thresholds required to induce damag
e with respect to distance and incident angle suggests that the mechan
ism of Ho:YAG lithotripsy is thermal.