Gi. Meniru et Il. Craft, UTILIZATION OF RETRIEVED OOCYTES AS AN INDEX OF THE EFFICIENCY OF SUPEROVULATION STRATEGIES FOR IN-VITRO FERTILIZATION TREATMENT, Human reproduction, 12(10), 1997, pp. 2129-2132
An analysis of 581 in-vitro fertilization treatment cycles was carried
out to determine the pattern of utilization of retrieved oocytes. Pat
ients were divided into five groups depending on the number of retriev
ed oocytes. The mean fertilization rate of 57% was broadly similar amo
ngst the groups but the proportion of retrieved oocytes that produced
embryos of a quality suitable for transfer or cryopreservation (the cy
cle efficiency index) fell significantly with increase in the retrieve
d oocyte number. However, the pregnancy rate increased with the number
of retrieved oocytes (13-38%). It is important to determine the point
at which advantages of multifollicular development are outweighed by
the potential for complications. Increased utilization of retrieved oo
cytes will decrease the need for production of a large number of oocyt
es.