While there are concerns about the consequences of widespread use of q
uinolones, there are few reports of quinolone-resistant strains of Sal
monella typhi or Salmonella paratyphi from the Indian subcontinent. We
present a case report of a newborn with meningitis due to a quinolone
-resistant strain of S. paratyphi B presenting to the Aga Khan Univers
ity Hospital (AKUH).