INFLUENCE OF DIAGNOSTIC CONIZATION ON SURGICAL MORBIDITY AND SURVIVALIN PATIENTS UNDERGOING RADICAL HYSTERECTOMY FOR STAGE IB AND IIA CERVICAL-CARCINOMA
Rak. Samlal et al., INFLUENCE OF DIAGNOSTIC CONIZATION ON SURGICAL MORBIDITY AND SURVIVALIN PATIENTS UNDERGOING RADICAL HYSTERECTOMY FOR STAGE IB AND IIA CERVICAL-CARCINOMA, European journal of gynaecological oncology, 18(6), 1997, pp. 478-481
The purpose of this retrospective study was to investigate whether dia
gnostic conization influenced surgical morbidity of a subsequent radic
al hysterectomy in patients with early cervical carcinoma. Furthermore
, the impact of an irradical conization on nodal metastases and progno
sis was analysed, Included were 271 patients with stage IB and IIA cer
vical carcinoma who underwent an Okabayashi radical hysterectomy betwe
en 1982 and 1991. There were 68 patients who underwent conization prio
r to medical hysterectomy. The conization-radical hysterectomy interva
l was approximately six weeks. Surgical morbidity in patients with a p
revious conization was not significantly different from that in patien
ts without a previous conization. Survival was also not significantly
different between these groups (95% vs. 91%, p = 0.23). Multivariate a
nalysis showed that tin irradical conization was not associated with a
n increased risk for nodal metastases or a poorer prognosis. We sugges
t that in early cervical carcinoma, a diagnostic conization does not a
dversely affect early morbidity of a following radical hysterectomy. A
n irradical conization does not seem to influence prognosis.