Bacteraemia of oral origin may result in infective endocarditis in sus
ceptible individuals. The aim of this pilot study was to investigate t
he occurrence of bacteraemia due to periodontal probing. Thirty patien
ts (15 male, 15 female; mean age 42.7 years) with untreated periodonti
tis were investigated. All were free of significant medical disorders
and none had taken antibiotics in the previous month. Prior to and imm
ediately following periodontal probing, 20 mL of venous blood were obt
ained from each patient and inoculated into aerobic and anaerobic bloo
d culture bottles and incubated. Negative bottles were monitored conti
nuously for three weeks before being discarded. Periodontal probing co
nsisted of measuring pockets at six points around each tooth and recor
ding the presence or absence of bleeding. A positive bacteraemia was r
ecorded for three of the patients prior to probing. One patient exhibi
ted Prevotella species whilst two exhibited skin commensals. Following
probing, 13 patients (43 per cent) exhibited bacteraemia of oral orig
in. Viridans streptococci were the most common isolates (45 per cent).
No significant correlations were found between bacteraemia and the se
verity of periodontitis or extent of bleeding on probing. The results
indicate that periodontal probing can cause bacteraemia in patients wi
th periodontitis. It would be advisable for patients considered at ris
k of developing infective endocarditis to receive antibiotic prophylax
is for periodontal probing if they have radiographic evidence of perio
dontitis.