1-SUBSTITUTED 3-DIMETHYLAMINOPROP-2-EN-1-ONES AS BUILDING-BLOCKS IN HETEROCYCLIC SYNTHESIS - ROUTES TO 6-ARYL-2H-PYRAN-2-ONE AND 6-HETEROARYL-2H-PYRAN-2-ONE AND 6-ARYLPYRIDIN-2(1H)-ONE AND 4-ARYLPYRIDIN-2(1H)-ONE

Authors
ALOMRAN F ALAWADHI N KHALIK MMA KAUL K ABUELKHAIR A ELNAGDI MH
Citation
F. Alomran et al., 1-SUBSTITUTED 3-DIMETHYLAMINOPROP-2-EN-1-ONES AS BUILDING-BLOCKS IN HETEROCYCLIC SYNTHESIS - ROUTES TO 6-ARYL-2H-PYRAN-2-ONE AND 6-HETEROARYL-2H-PYRAN-2-ONE AND 6-ARYLPYRIDIN-2(1H)-ONE AND 4-ARYLPYRIDIN-2(1H)-ONE, Journal of chemical research. Synopses, (3), 1997, pp. 84
Citations number
21
Categorie Soggetti
Chemistry
Journal title
Journal of chemical research. Synopses → ACNP
ISSN journal
03082342
Issue
3
Year of publication
1997
Database
ISI
SICI code
0308-2342(1997):3<84:13ABIH>2.0.ZU;2-B
Abstract
Several new 6-substituted-3-acylamino-2H-pyran-2-ones 6a-j have been p repared from the reaction of enaminones 4a-f with N-acyl- and N-benzoy l-glycines; the enaminones 4a-c react with malononitrile in ethanol so lution and in the presence of a base to yield amides 11a-c which are c onverted into 6-aryl-1,2-dihydro-2-oxypyridine-3-carbonitriles 13a-c o n reflux in acetic acid.