Ja. Tolomeo et Cr. Steele, A DYNAMIC-MODEL OF OUTER HAIR CELL MOTILITY INCLUDING INTRACELLULAR AND EXTRACELLULAR FLUID VISCOSITY, The Journal of the Acoustical Society of America, 103(1), 1998, pp. 524-534
The deformation response of a guinea pig outer hair cell is modeled fo
r mechanical and electrical stimulation up to 25 kHz. The analysis use
s a Fourier series technique for a finite length cell surrounded inter
nally and externally by a much larger continuum of viscous fluid. The
analytical solution predicts that outer hair cell length changes occur
due to applied mechanical or electrical stimulation without significa
nt resonance, characteristic of a highly damped system. The deformatio
n is found to have little attenuation up to a corner frequency of abou
t 2 kHz for long cells and 10 kHz for short cells, in agreement with p
ublished experimental results. For electrical loading of 1 mV across t
he lateral cell wall, deformation for short cells is calculated to be
greater than 1 nm for frequencies up to 20 kHz. These results support
the proposition that in vivo the outer hair cell modifies the characte
r of basilar membrane deformation on a cycle-by-cycle basis. An estima
te of the capability of the cell to supply energy to the basilar membr
ane is given based on published values of outer hair cell material pro
perties. (C) 1998 Acoustical Society of America.