Colorectal canter is usually revealed by modifications of bowel habit
and/or signs of haemorrhage. Hepatic and lung metastases are the commo
n sites of metastatic involvement of this cancer. Brain metastasis are
rare, especially when they are isolated. We report the case of a 37-y
ear-old patient presenting with isolated brain metastasis revealing a
rectal cancer. The patient was initially treated by surgical excision
of the symptomatic brain metastasis, followed several days later by an
terior resection of the rectum and whole-brain radiotherapy. This unus
ual strategy, due to the lack of preoperative diagnosis, did not impro
ve the poor prognosis of brain metastasis.