Malaria remains the most important of the tropical diseases, widesprea
d throughout the tropics, but also occurring in many temperate regions
. The disease causes a heavy toll of illness and death, especially amo
ng children in endemic areas. It also poses a risk to business travell
ers, tourists and inmigrants and imported cases of malaria are increas
ingly seen in non-endemic areas. We discuss here how microscopical dia
gnosis is essential for identifying Plasmodium species responsible of
the infection and discarding possible mixed infections. Thus, a correc
t treatment can be administered in 30 min, avoiding secondary stays an
d saving important amounts of money. Problems of drug resistance have
to be distinguished from those arising due to erroneous diagnosis.