Bone scintigraphy of the hands and wrists represents an important adju
nct imaging technique that complements plain film radiographic examina
tion. The use of the three-phase bone scan provides clinical informati
on not only regarding osseous uptake but the blood flow and extravascu
lar distribution of the radiotracer as well. Scintigraphic evaluation
of the hands and wrists is employed in acute and chronic conditions. I
n the event of an equivocal or negative plain film, the bone scan can
identify occult fractures. Of particular concern is the identification
of scaphoid fractures due to the higher incidence of osteonecrosis. W
ork related injuries represent a significant health issue. The bone sc
an can be a part of the algorithm for evaluating chronic pain syndrome
s including reflex sympathetic dystrophy. The complimentary roles of b
one scanning and imaging with gallium-67 citrate or radiolabeled leuko
cytes has proven useful in the evaluation of acute or chronic osteomye
litis. In addition, the diphosphonates are useful in identifying solit
ary and multiple primary bone tumors. In the case of primary bone tumo
r, thallium-201 can be used to evaluate response to therapy. Although
uncommon in the hand and wrist, the bone scan can identify metastatic
tumors or tumor related conditions such as hypertrophic osteoarthropat
hy, Finally, bone scintigraphy may be useful in identifying location a
nd extent in a variety of conditions such as fibrous dysplasia, histio
cytosis X, and Paget's disease. Copyright (C) 1998 by W.B. Saunders Co
mpany.