DIFFERENCES IN ION PERMEABILITY OF AN ARTIFICIAL BILAYER-MEMBRANE CAUSED BY AMPULLOSPORIN AND BERGOFUNGIN, NEW 15-MEMBERED PEPTAIBOL-TYPE ANTIBIOTICS

Authors
GRIGORIEV PA BERG A SCHLEGEL R GRAFE U
Citation
Pa. Grigoriev et al., DIFFERENCES IN ION PERMEABILITY OF AN ARTIFICIAL BILAYER-MEMBRANE CAUSED BY AMPULLOSPORIN AND BERGOFUNGIN, NEW 15-MEMBERED PEPTAIBOL-TYPE ANTIBIOTICS, Bioelectrochemistry and bioenergetics, 44(1), 1997, pp. 155-158
Citations number
12
Categorie Soggetti
Biology,Biophysics,"Biology Miscellaneous
Journal title
Bioelectrochemistry and bioenergetics → ACNP
ISSN journal
03024598
Volume
44
Issue
1
Year of publication
1997
Pages
155 - 158
Database
ISI
SICI code
0302-4598(1997)44:1<155:DIIPOA>2.0.ZU;2-L
Abstract
The membrane activity of new 15-membered peptaibol-type antibiotics, a mpullosporin (I) from Sepedonium ampullosporum and bergofungin (II) fr om Emericellopsis donezkii, was tested by use of an artificial bilayer membrane, Bergofungin (II) conveys protons more efficiently than ampu llosporin (I) suggesting that the-nature and the sequence of the const ituting amino acids determine their special effect on ion penetration. (C) 1997 Elsevier Science S.A.