METABOLIC THERAPY OF ISCHEMIC STROKE - AP PLICATION OF NOOTROPIL

54 patients were treated by nootropil (pyracetam). The results of ther apy were evaluated statistically according to a number of clinical sca les and neurophysiologic indices (EEG and evoked potentials with mappi ng of bioelectric activity). The results were compared with the data a bout 56 patients of the control group which were treated by traditiona l method without application of nootropil. Nootropil was applied by tw o ways: small doses (4-12 g dally) during 5 days or high doses (10-12 g daily) during 30 days from the moment when the patient admitted Po t he hospital. Intravenous injections of the drug were used in all cases as well as its internal administration. It was showed either efficien cy of the drug, especially in high doses, in early beginning of the tr eatment and its duration for at least 30 days or goad tolerance of the drug. Authors supposed that application of pyracetam is not adequate in strokes with severe disorders of consciousness and cerebral edema.