Gs. Burd et al., NOOTROPIL IN TREATMENT OF DISORDERS OF HI GH MENTAL FUNCTIONS IN PATIENTS WITH ISCHEMIC STROKE, Zurnal nevropatologii i psihiatrii im. S.S. Korsakova, 97(10), 1997, pp. 29-34
47 patients with acute ischemic stroke were treated with nootropil (py
racetam, UCB, Belgium) from the first day of the disease (12 g, intrav
enously, by drops during 2 weeks, then 4.8 g, per os) on the backgroun
d of basic therapy. There was revealed increase of spontaneus activity
, expressive and impulsive speech, audio-and speaking memory (especial
ly delayed memory), tactile, acustic and visual gnosis, space praxis.
There was observed more pronounced positive dynamics of functions of d
amaged hemisphere in patients with localisation of ischemic focus in l
eft hemisphere. Meanwhile restoration was slower when ischemic focus w
as localized in right hemisphere, Restoration of high mental functions
occured to be faster during nootropil treatment as compared with basi
c therapy only. The conclusion was made that nootropil can be prescrip
ted for the patients with hemispheric ischemic stroke and especially f
or the patients with alterations of cerebral circulation in system of
internal carotid artery including such disturbances on the background
of insufficiency of circulation in vertebrobasilar system.