NOVEL ROUTE TO THE SYNTHESIS OF HYDROXYLATED PYRROLIDINE DERIVATIVES VIA THE INTRAMOLECULAR REACTION OF GAMMA-AMINOALLYSTANNANE WITH ALDEHYDE - TOTAL SYNTHESIS OF (-PREUSSIN())
I. Kadota et al., NOVEL ROUTE TO THE SYNTHESIS OF HYDROXYLATED PYRROLIDINE DERIVATIVES VIA THE INTRAMOLECULAR REACTION OF GAMMA-AMINOALLYSTANNANE WITH ALDEHYDE - TOTAL SYNTHESIS OF (-PREUSSIN()), Heterocycles, 46, 1997, pp. 335-348
The thermal cyclization of gamma-aminoallylstannane (8) having an alde
hyde group gave beta-hydroxypyrrolidine derivative (9a) as a sole prod
uct. This methodology was applied successfully to the total synthesis
of (+)-preussin.